Tissue Sections

TIRF microscopy offers a unique advantage for imaging tissue sections by visualizing intricate details with high precision. TIRF selectively illuminates a thin section near the surface of the tissue, reducing background noise, and providing increased clarity of cellular structures within the sample. This technique is especially valuable for studying tissue architecture at the subcellular level. 

Fish Intestine

A tissue section of a fish intestine can be seen below. The intestine is a multifunctional organ, susceptible to significant and rapid functional and structural changes in response to various dietary factors. Consequently, histology serves as a method to evaluate the overall impact of fish feed, and helps evaluate the effect on intestinal function.


The tissue sample below was stained for nucleus (left), and actin (middle). The composite image can be seen on the right.